Beilstein J. Org. Chem.2021,17, 1001–1040, doi:10.3762/bjoc.17.82
: amidine; biguanide; guanidine chemistry; metforminderivatives; polynitrogen ligands; synthetic methodology; Introduction
Biguanide – or amidinoguanidine – is a chemical compound derived from guanidine in which two guanidine molecules are linked through a common nitrogen atom. Since its first synthesis